Ghana deputy captain Andre Dede Ayew will start in place of injured Andy Carroll for tonight's clash with Tottenham Hotspurs.
Carroll was a serious doubt for the Hammers going into this clash, and the towering striker has failed to overcome groin problem, so Andre Ayew leads the line for Slaven Bilic’s side.
Meanwhile, captain Mark Noble returns to the team.
Walker comes back into the Spurs team with his long-term future at Tottenham hanging in the balance.
Mauricio Pochettino batted away questions on Thursday as mere speculation, but only time will tell how many more appearances he will make for the club.
Here are the teams in the full.
Starting line-ups
West Ham XI: Adrian, Collins, Reid, Fonte, Byram, Noble, Kouyate, Cresswell, Lanzini, Ayew, Calleri
Substitutes: Randolph, Nordtveit, Feghouli, Snodgrass, Fletcher, Fernandes, Rice.
Tottenham XI: Lloris, Dier, Alderweireld, Vertonghen, Walker, Wanyama, Eriksen, Davies, Alli, Son, Kane
Substitutes: Janssen, Vorm, Nkoudou, Trippier, Sissoko, Wimmer, Dembele.