Östersund FC will be missing the services of Ghanaian duo Frank Arhin and Patrick Kpozo following their failure to secure visas to Ukraine for the game on Thursday,
Ostersunds are in Group J alongside Hertha Berlin, Athletic Bilbao and Zorya Luhansk.
They will begin their group stage campaign on Thursday with a game against Ukrainian outfit Zorya Luhansk away from home.
"Frank and Patrick could not follow for visa reasons," said chairman Daniel Kindberg to the football channel.
"Frank and Patrick are home for visa reasons," says ÖFK's chairman Daniel Kindberg.
"It feels great. This is a very exciting experience and a real experience, says the chairman.
"You always feel when you get closer to the game that players get into a stronger focus. They have been practicing for a long time just to change the focus.