Hearts of Oak aim to grab their first win of the campaign as they travel to face WAFA.
The Phobians, who come into the season as defending champions, were held to a 0-0 draw by Legon Cities in Accra.
WAFA on the other hand, conceded a late goal in a 1-0 defeat against King Faisal and will be looking to make amends on Friday.
In the last five meetings between the two teams, Hearts of Oak have recorded two victories and one defeat. However, the Phobians have never been successful at WAFA, a statline they will hope to change on Friday.
Prediction: WAFA 1-2 Hearts