The Ghana Football Association have confirmed that Black Stars second group match will kick off at 1:00pm on Monday away to Sao Tome.
The two countries are on the same time zone so there will not be issues of time differences for fans.
The match is the second for Ghana in the qualifiers after they beat South Africa 2-0 on Thursday in Cape Coast.
The team will hope to get a good result to give them a good footing ahead of the resumption of qualifiers in 2020.