Dreams aim to get their first victory in the 2020/21 season as they welcome Medeama to Dawu.
The Still Believe boys had a disappointing start to the campaign, taking only a 0-0 draw from Inter Allies despite the improved firepower in attack.
Medeama also started the season in a disappointing note, drawing 1-1 with Great Olympics on home soil despite the quality they possessed on the pitch.
They will hope to grab their first victory of the season against Dreams.
In their last four battles, Medeama have been the better side with two victories and one defeat. The Mauve and Yellows will go into the tie with some confidence.
Prediction: Dreams 0-2 Medeama