Milovan Rajevac and his men will aim to build on Saturday's performance with another victory over Zimbabwe away from home on Tuesday.
At the Accra Sports Stadium, the Black Stars showed real superiority, clinching a 3-1 victory over their upcoming opponents.
With World Cup qualification still in the balance, the senior national team will hope to get a positive result.
Preview
So far, the Black Stars have recorded two victories and one loss in Group G. The two wins came against Ethiopia and Zimbabwe whilst the defeat came at the hands of South Africa.
Milo's side are currently second on the log, just one point behind table-toppers South Africa.
Zimbabwe have endured a poor start to qualification, losing two of their three games so far and failing to grab any victory.
Both sides will hope to get a result after the game kicks off at 1PM.
Team news
Ghana are currently sweating on the fitness of Baba Iddrisu who picked up a knock in training. Milo will be hopeful that the midfielder recovers quickly enough to play.
Ghana XI: Wollacott, Amartey, Djiku, Jonathan Mensah, Baba Rahman, Partey, Iddrisu, Kamaldeen, Kudus, Andre Ayew, Jordan Ayew
Zimbabwe can now call on the services of Khama Billiat who has served his suspension.
Zimbabwe XI: Shumba; Chimwemwe, Bhasera, Mudimu, Lunga; Chikwende, Nakamba, Munetsi, Dzvukamanja, Billiat; Musona
Prediction
It will certainly be a tough clash for the Black Stars but they are expected to grab a tightly contested win.
Zimbabwe 0-1 Ghana