The Ghanaian quartet at Fortuna Düsseldorf will play under a new coach for the rest of the season after head coach Friedhelm Funkel was sacked on Wednesday.
Kasim Nuhu, Bernard Tekpetey, Kelvin Ofori and Nana Ampomah will now train under Uwe Rösler.
Funkel has paid for Fortuna Düsseldorf's downward spiral in the Bundesliga.
The 66-year-old signed a contract extension last December but with the club at the bottom of the table, his position became untenable.
Fortuna Düsseldorf lost their last two matches against Werder Bremen and Bayer Leverkusen.