It is Uzbek Irmatov's second match at Russia 2018, having officiated the Group D tie between Argentina and Croatia on June 21.
The five-time AFC Referee of the Year is appearing in his third FIFA World Cup and is assisted by compatriots Abdukhamidullo Rasulov and Jakongir Saidov for the Spain-Morocco tie.
Asia's Mohammed Mohammed Abdulla, who refereed the Group C tie between France and Peru on June 21, is the fourth official and Mohamed Alhammadi the fifth official. Both are from the United Arab Emirates.
Bahrain's Nawaf Abdulla Shukralla was tasked with refereeing the Group H tie between Poland and Senegal on June 19 while Alireza Faghani of the Islamic Republic of Iran handled the Group F tie between Germany and Mexico on June 17.
Besides on field duties, numerous Asians have been involved as fourth, fifth officials and VAR referees at the FIFA World Cup.
Asian Match Officials
Nawaf Shukralla (BHR): Serbia v Switzerland
Ryuji Sato (JPN): Portugal v Spain; Belgium v Panama; Germany v Sweden
Mohammed Mohammed Abdulla (UAE): Germany v Mexico; Spain v Morocco
Abdulrahman Al Jassim (QAT): Poland v Senegal; Japan v Senegal
Yaser Tulefat (BHR): Serbia v Switzerland
Toru Sagara (JPN): Portugal v Spain; Belgium v Panama; Germany v Sweden
Hiroshi Yamauchi (JPN): Tunisia v England; Nigeria v Iceland; Saudi Arabia v Egypt
Mohamed Alhammadi (UAE): Germany v Mexico; Poland v Senegal; Spain v Morocco
Hasan Almahri (UAE): Uruguay v Russia
Taleb Al Marri (QAT): Japan v Senegal
Abdulrahman Al Jassim (QAT): Sweden v Korea; France v Peru
Taleb Al Marri (QAT): Sweden v Korea; France v Peru