The MTN FA Cup enters the Round of 16 stage on Friday with West Africa Football Academy hosting Emmanuel FC in an intriguing tie at the Sogakope WAFA Park.
WAFA are yet to lose at home since returning to the topflight and will be expected to continue their fine form against lower-tier Emmanuel FC who are bankrolled by Nigerian televangelist, Temitope Balogun Joshua.
Wa Rockets will also welcome Asokwa Deportivo to the Wa Stadium the same day.
On Saturday, Storm Academy host Kumasi Asante Kotoko at the Nkawkaw Park, while giant-killers FC Samartex 1996, who kicked out Hearts of Oak, play Liberty Professionals at Samreboi.
On Sunday, Okwawu United clash with Sekondi Hasaacas at Nkawkaw; Real Tamale United host Bechem United at the Tamale Stadium, Wa All Stars welcome Mighty Royals to the Wa Stadium, and Elmina Sharks battle True Democracy at the Nduom Stadium in Elmina.