Medeama SC can reach the CAF Confederation Cup semi-finals on Tuesday by grabbing just a point to finish second in Group A.
The Tarkwa based side are away to play MO Bejaia in Algeria and can only go through with a win or any form of a draw.
Medeama moved three points above Bejaia with a thrilling 3-2 home victory over group leaders TP Mazembe of the Democratic Republic of Congo this month.
Kwesi Donsu snatched the winner five minutes into stoppage time after one of the most entertaining matches in the 13-year history of the second-tier African club competition.
"I pray that we can repeat that performance against Bejaia," said coach Prince Owusu,
"Such is the calibre of the footballers at Mazembe that I call them 'Africa United'. They came to beat us, but we shocked them.
"We have had a tough CAF campaign with many off-pitch problems -- especially a lack of funds for travelling -- but extremely hard work has taken us within sight of the semi-finals."
For MO Bejaia a 1-0 victory over visiting Medeama will take the North Africans through on the head-to-head rule despite the goal drought.
The North Africans forced a 0-0 draw at Medeama and will jump from third to second in the standings if they collect maximum points at home.
"We will fight with all our power to win the last group game," promised Bejaia coach and former Algeria defender Nacer Sandjak.
"Losing at Young Africans was an unexpected setback and we have no option but to go all out against Medeama and achieve victory."
Mazembe, whose squad includes stars from DR Congo, Ghana, Ivory Coast, Mali, Tanzania and Zambia, need one point against visiting Young Africans to be certain of topping the final standings.