Ghana captain Andre Ayew was left broken hearted following Black Stars defeat to Portugal in the 2022 World Cup opener.
The Al Sadd star who was subbed off after restoring parity in the second half of the much-anticipated clash on Thursday.
Cristiano Ronaldo became the first player in World Cup history to score five times, with his second-half penalty giving Portugal the lead.
Ghana's Andre Ayew then equalized, but two goals in three minutes from Joao Felix and Rafael Leao secured the victory and moved Portugal to the top of Group H, despite Osman Bukari's late winner.
After the game, the most capped player for Ghana took to social media to express how shocked he is with the defeat.
The 2016 European Champions currently sit top of Group H with three points.
Meanwhile, the defeat means Ghana are bottom of Group H after Uruguay and South Korea played out a goalless draw earlier on Thursday.
The Black Stars will now turn their attention to their upcoming matches against South Korea and Uruguay on November 28 and December 2, respectively.