Lazio travel to the Stadio Via del Mare for their 30th Serie A meeting with Lecce.
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Having won their last three trips to Lecce, Lazio are also unbeaten in their last 15 meetings against newly promoted teams.
Lecce, meanwhile, have lost their last six Serie A games, their worst run in the top flight since February 1998.
Lecce:
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Lazio: Strakosha; Patric, Acerbi, Radu; Lazzari, Parolo, Lucas Leiva, Luis Alberto, Jony; Immobile, Caicedo.
Source: forzaitalianfootball.com