Otto Addo says he is hurting after failing to led Ghana past the group stage of the 2022 World Cup in Qatar.
Black Stars skipper Andre Ayew missed a penalty in the 21st minute as his kick was saved by Uruguay goalkeeper Sergio Rochet following a foul on Mohammed Kudus.
Uruguay went on to win the game 2-0 thanks to goals from Giorgio de Arrascaeta in the 26th and 32nd minutes of the game but it was not enough as teams went out of the tournament.
"What hurts the most is that we're out," coach Addo said after the game.
"I know the public sought revenge but I don't think this way, and I told the players they should not as well.
"I am a strong believer that if you do not seek revenge, you will get more blessings. If it was not Uruguay, we would have tried against another team.
"It was not important. We were prepared, but today the luck was not on our side. We could have prevented both goals, this is where we have to learn.
"Sometimes you are so close to taking one step further, but then you concede and it gets into your mind. To come back out of this is very difficult.
"We did it against South Korea but today we couldn't do it, the second goal came way too early.
"We created a lot of chances, at the end we could have conceded a third goal. I believed until the end that we could score."